Debra Lynn Messing (born August 15, 1968) is an American actress. After graduating from New York University's Tisch School of the Arts, Messing appeared in several television series, including Ned and Stacey on Fox (1995–1997) and Prey on ABC (1998). She achieved her breakthrough role as Grace Adler, an interior designer, on the NBC sitcom Will & Grace (1998–2006, 2017–2020), for which she received seven Golden Globe Award nominations and five Primetime Emmy Award nominations for Outstanding Lead Actress in a Comedy Series, winning once, in 2003.

From 2007 to 2008, Messing starred as Molly Kagan, the ex-wife of a Hollywood film mogul, on the television miniseries The Starter Wife, for which she received two Golden Globe nominations, a Primetime Emmy Award nomination, and a Screen Actors Guild Award nomination. Thereafter, she appeared as Broadway playwright Julia Houston on the NBC musical drama Smash (2012–2013) and as homicide detective Laura Diamond on the NBC police-procedural comedy The Mysteries of Laura (2014–2016). From 2017 to 2020, Messing reprised her role as Grace Adler on NBC's three season revival of Will & Grace, garnering a ninth Golden Globe nomination for her performance.

Messing's film work includes A Walk in the Clouds (1995), Jesus (1999), The Mothman Prophecies (2002), Hollywood Ending (2002), Along Came Polly (2004), The Wedding Date (2005), Lucky You (2007), The Women (2008), Nothing Like the Holidays (2008), Searching (2018), and 13: The Musical (2022). She has also lent her voice to animated films such as Garfield (2004) and Open Season (2006).